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JACKFRUIT Overview Uses Side Effects PrecautionInteractionDosing and Reviews

JACKFRUITOverviewUsesSideEffectsPrecautionsInteractionsDosingandReviews

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OTHER NAME(S): Arbol Del Pan, Artocarpus heterophyllus, Baramil, Bo Luo Mi, Cakki, Chakka, Derakhte Nan, Falso Albero Del Pane, Fenesi, Finesy, Fruta Del Pobre, Halasina Hannu, Halasu, Indischer Brotfruchtbaum, Jaca, Jack, Jackfrucht, Jackfrugttrae, Jackfrukt, Jacktrad, Jacquier, Jak, Jaka, Jaqueira, Jaqueiro, Katahal, Kathal, Kanthal, Keledang, Khanun, Khnor, Konthal, Konto Phol, Kontok Phol, Kontoki, Kontoki Phol, Kos, Langka, Maak Laang, Mai Mi, Mak Mi, Makmee, Mu Bo Luo, Nagami Pannoki, Nangka, Palaa, Palavu, Panasa, Panasah, Panasam, Panasero, Paramitsu, Phanas, Phannasa, Pholkontok, Rukh Kutaherr, Shu Bo Luo.

OTHER NAME(S): Arbol Del Pan, Artocarpus heterophyllus,

Jackfruit is a tree. People eat the fruit and seeds of jackfruit tree as food or as medicine.

Jackfruit is taken bymouthas an aphrodisiac or fordiabetes.

Jackfruit paste is applied to theskinfor poisonous bites.

Also, the wood of the jackfruit tree is used to make furniture or musical instruments.

Jackfruit might help people with diabetes by lessening post-meal increases in blood sugar.

Diabetes. Early research suggests that taking jackfruit extract before a meal may lessen post-meal increases inblood sugar levelsin people with diabetes.

More evidence is needed to rate the effectiveness of jackfruit for these uses.

It isnt known if jackfruit is safe when taken as a medicine. The fruit of jackfruit might cause allergic reactions in some people.

: Not enough is known about the use of jackfruit during pregnancy and breast-feeding. Stay on the safe side and avoid use.

: Some people who are allergic to birchpollenor latex might also be allergic to jackfruit.

: Jackfruit might lowerblood sugar levels. There is a concern that it might affectblood sugarcontrol in people with diabetes. The dose of diabetes medication might need to be changed.

: Jackfruit might cause too much drowsiness if combined withmedicationsused during and after surgery. Stop taking jackfruit at least 2 weeks before a scheduled surgery.

Jackfruit might lower blood sugar. Diabetes medications are also used to lower blood sugar. Taking jackfruit with diabetes medications might cause your blood sugar to be too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.

Jackfruit might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking jackfruit along with sedative medications might cause too much sleepiness.Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.

The appropriate dose of jackfruit for use as treatment depends on several factors such as the users age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for jackfruit. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult yourpharmacistor physician or otherhealthcareprofessional before using.

Alila P, Sanyal D. Jackfruit in northern and eastern India. The Jackfruit. Ed. Valvi SG, Peter KV, Thottappilly G. New Delhi: Studium Press, 2011. 409-420.

Barua AG, Boruah BR. Minerals and functional groups present in the jackfruit seed: a spectroscopic investigation. Int J Food Sci Nutr 2004;55(6):479-483. View abstract.

Blasco E, Ngoc LD, Aucouturier P, PreudHomme JL, Barra A. Mitogenic activity of new lectins from seeds of wild Artocarpus species from Vietnam. C R Acad Sci III 1996;319(5):405-409. View abstract.

Bolhaar ST, Ree R, Bruijnzeel-Koomen CA, Knulst AC, Zuidmeer L. Allergy to jackfruit: a novel example of Bet v 1-related food allergy. Allergy 2004;59(11):1187-1192. View abstract.

Bunn-Moreno MM, Campos-Neto A. Lectin(s) extracted from seeds of Artocarpus integrifolia (jackfruit): potent and selective stimulator(s) of distinct human T and B cell functions. J Immunol 1981;127(2):427-429. View abstract.

Bunn-Moreno MM, Campos-Neto A. Lectin(s) extracted from seeds of Artocarpus integrifolia (jackfruit): potent and selective stimulator(s) of distinct human T and B cell functions. J Immunol 1981;127(2):427-429. View abstract.

Fernando MR, Wickramasinghe N, Thabrew MI, Ariyananda PL, Karunanayake EH. Effect of Artocarpus heterophyllus and Asteracanthus longifolia on glucose tolerance in normal human subjects and in maturity-onset diabetic patients. J Ethnopharmacol 1991;31(3):277-282. View abstract.

Hagiwara K, Collet-Cassart D, Kobayashi K, Vaerman JP. Jacalin: isolation, characterization, and influence of various factors on its interaction with human IgA1, as assessed by precipitation and latex agglutination. Mol Immunol 1988;25(1):69-83. View abstract.

Kabir S, Aebersold R, Daar AS. Identification of a novel 4 kDa immunoglobulin-A-binding peptide obtained by the limited proteolysis of jacalin. Biochim Biophys Acta 1993;1161(2-3):194-200. View abstract.

Kabir S, Daar AS. The composition and properties of jacalin, a lectin of diverse applications obtained from the jackfruit (Artocarpus heterophyllus) seeds. Immunol Invest 1994;23(3):167-188. View abstract.

Khan MR, Omoloso AD, Kihara M. Antibacterial activity of Artocarpus heterophyllus. Fitoterapia 2003;74(5):501-505. View abstract.

Lakheda S, Devalia R, Jain UK, et al. Anti-inflammatory activity of Artocarpus heterophyllus bark. Der Pharmacia Sinica 2011;2(2):127-130.

Ratnasooriya WD, Jayakody JR. Artocarpus heterophyllus seeds inhibits sexual competence but not fertility of male rats. Indian J Exp Biol 2002;40(3):304-308. View abstract.

Roque-Barreira MC, Campos-Neto A. Jacalin: an IgA-binding lectin. J Immunol 1985;134(3):1740-1743. View abstract.

Soares MB, Armada JL, Soares VM, Seuanez HN. Artocarpus integrifolia lectin(s): use and applications in chromosome studies of lymphocyte cultures. Cytobios 1982;34(135-36):165-174. View abstract.

Tachibana K, Nakamura S, Wang H, et al. Elucidation of binding specificity of Jacalin toward O-glycosylated peptides: quantitative analysis by frontal affinity chromatography. Glycobiology 2006;16(1):46-53. View abstract.

Thomas CA. Jackfruit, Artocarpus heterophyllus (Moraceae), as source of food and income. Econ Bot 1980;34(2):154-159.

Trindade MB, Lopes JL, Soares-Costa A, et al. Structural characterization of novel chitin-binding lectins from the genus Artocarpus and their antifungal activity. Biochim Biophys Acta 2006;1764(1):146-152. View abstract.

Wetprasit N, Threesangsri W, Klamklai N, Chulavatnatol M. Jackfruit lectin: properties of mitogenicity and the inhibition of herpesvirus infection. Jpn J Infect Dis 2000;53(4):156-161. View abstract.

Alila P, Sanyal D. Jackfruit in northern and eastern India. The Jackfruit. Ed. Valvi SG, Peter KV, Thottappilly G. New Delhi: Studium Press, 2011. 409-420.

Blasco E, Ngoc LD, Aucouturier P, PreudHomme JL, Barra A. Mitogenic activity of new lectins from seeds of wild Artocarpus species from Vietnam. C R Acad Sci III 1996;319(5):405-409. View abstract.

Bolhaar ST, Ree R, Bruijnzeel-Koomen CA, Knulst AC, Zuidmeer L. Allergy to jackfruit: a novel example of Bet v 1-related food allergy. Allergy 2004;59(11):1187-1192. View abstract.

Bunn-Moreno MM, Campos-Neto A. Lectin(s) extracted from seeds of Artocarpus integrifolia (jackfruit): potent and selective stimulator(s) of distinct human T and B cell functions. J Immunol 1981;127(2):427-429. View abstract.

Bunn-Moreno MM, Campos-Neto A. Lectin(s) extracted from seeds of Artocarpus integrifolia (jackfruit): potent and selective stimulator(s) of distinct human T and B cell functions. J Immunol 1981;127(2):427-429. View abstract.

Fang SC, Hsu CL, Yen GC. Anti-inflammatory effects of phenolic compounds isolated from the fruits of Artocarpus heterophyllus. J Agric Food Chem. 2008;56(12):4463-8. View abstract.

Fernando MR, Wickramasinghe N, Thabrew MI, Ariyananda PL, Karunanayake EH. Effect of Artocarpus heterophyllus and Asteracanthus longifolia on glucose tolerance in normal human subjects and in maturity-onset diabetic patients. J Ethnopharmacol 1991;31(3):277-282. View abstract.

Hagiwara K, Collet-Cassart D, Kobayashi K, Vaerman JP. Jacalin: isolation, characterization, and influence of various factors on its interaction with human IgA1, as assessed by precipitation and latex agglutination. Mol Immunol 1988;25(1):69-83. View abstract.

Hettiaratchi UP, Ekanayake S, Welihinda J. Nutritional assessment of a jackfruit (Artocarpus heterophyllus) meal. Ceylon Med J. 2011;56(2):54-8. View abstract.

Kabir S, Aebersold R, Daar AS. Identification of a novel 4 kDa immunoglobulin-A-binding peptide obtained by the limited proteolysis of jacalin. Biochim Biophys Acta 1993;1161(2-3):194-200. View abstract.

Kabir S, Daar AS. The composition and properties of jacalin, a lectin of diverse applications obtained from the jackfruit (Artocarpus heterophyllus) seeds. Immunol Invest 1994;23(3):167-188. View abstract.

Khan MR, Omoloso AD, Kihara M. Antibacterial activity of Artocarpus heterophyllus. Fitoterapia 2003;74(5):501-505. View abstract.

Lakheda S, Devalia R, Jain UK, et al. Anti-inflammatory activity of Artocarpus heterophyllus bark. Der Pharmacia Sinica 2011;2(2):127-130.

Prakash O, Kumar R, Mishra A, Gupta R. Artocarpus heterophyllus (Jackfruit): An overview. Phcog Rev [serial online] 2009 [Accessed: January 16, 2019];3:353-8. Available at:

Ratnasooriya WD, Jayakody JR. Artocarpus heterophyllus seeds inhibits sexual competence but not fertility of male rats. Indian J Exp Biol 2002;40(3):304-308. View abstract.

Roque-Barreira MC, Campos-Neto A. Jacalin: an IgA-binding lectin. J Immunol 1985;134(3):1740-1743. View abstract.

Siritapetawee J, Thammasirirak S. Purification and characterization of a heteromultimeric glycoprotein from Artocarpus heterophylluslatex with an inhibitory effect on human blood coagulation. Acta Biochim Pol. 2011;58(4):521-8. View abstract.

Siritapetawee J, Thumanu K, Sojikul P, Thammasirirak S. A novel serine protease with human fibrino(geno)lytic activities from Artocarpus heterophylluslatex. Biochim Biophys Acta. 2012;1824(7):907-12. View abstract.

Soares MB, Armada JL, Soares VM, Seuanez HN. Artocarpus integrifolia lectin(s): use and applications in chromosome studies of lymphocyte cultures. Cytobios 1982;34(135-36):165-174. View abstract.

Tachibana K, Nakamura S, Wang H, et al. Elucidation of binding specificity of Jacalin toward O-glycosylated peptides: quantitative analysis by frontal affinity chromatography. Glycobiology 2006;16(1):46-53. View abstract.

Thomas CA. Jackfruit, Artocarpus heterophyllus (Moraceae), as source of food and income. Econ Bot 1980;34(2):154-159.

Trindade MB, Lopes JL, Soares-Costa A, et al. Structural characterization of novel chitin-binding lectins from the genus Artocarpus and their antifungal activity. Biochim Biophys Acta 2006;1764(1):146-152. View abstract.

Wetprasit N, Threesangsri W, Klamklai N, Chulavatnatol M. Jackfruit lectin: properties of mitogenicity and the inhibition of herpesvirus infection. Jpn J Infect Dis 2000;53(4):156-161. View abstract.

Wongrakpanich S, Klaewsongkram J, Chantaphakul H, Ruxrungtham K. Jackfruit anaphylaxis in a latex allergic patient. Asian Pac J Allergy Immunol. 2015;33(1):65-8. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION:This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.

© Therapeutic Research Faculty 2020.

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